Strong Evidence

TB-500 for Dogs

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide in nearly all animal cells. Critical for tissue repair, cell migration, blood vessel formation, and inflammation regulation. Widely used in equine medicine for decades.

Wound HealingMobilityRecoveryInflammationTissue Repair

What Does the Research Say?

Extensive research in wound healing, cardiac repair, tissue regeneration. Promotes cell migration to injury sites, accelerates wound closure, supports new blood vessel formation, reduces inflammation and fibrosis. Decades of use in equine vet medicine. Growing application in dogs based on established veterinary track record.

Weight-Based Dosing Reference

⚠️ Important: Consult your veterinarian for dosing specific to your dog. This is reference information only.

SizeWeightBreeds
SmallUnder 25 lbsChihuahua, Dachshund, Pomeranian
Medium25–60 lbsBeagle, Border Collie, Cocker Spaniel
Large60–100 lbsLabrador, Golden Retriever, German Shepherd
GiantOver 100 lbsGreat Dane, Mastiff, Saint Bernard

🩺 Administration: Primarily injectable (subcutaneous). Oral bioavailability is significantly lower than BPC-157, making injectable the preferred format. Most protocols involve a loading phase (2-4 weeks) then maintenance. Vet-supervised.

Side Effects & Safety

Well-tolerated. Common: temporary lethargy after injection, mild injection site reactions, occasional nausea (transient). Use caution with known/suspected cancers due to pro-angiogenic properties.

⚠️ Tumor Caution: Peptides promoting tissue repair could theoretically accelerate existing tumors. Vet screening recommended before starting, especially for seniors and cancer-prone breeds.

Where to Get TB-500 for Dogs

🏪 Integrative Peptides (Pettides)

Pet-specific oral supplements. US-made, ≥99% purity, vet-recommended.

Full Review →

🩺 Long Companion Labs

Vet telehealth + Rx peptides from a 503A compounding pharmacy.

Full Review →

Related Conditions

Joint PainPost-SurgerySkin & Coat

FAQ

What is TB-500 used for in dogs?

Wound healing, tissue repair, post-surgical recovery, and mobility. Often paired with BPC-157.

Can TB-500 be given orally?

Most effective by injection. Oral bioavailability is significantly lower than BPC-157.

How long does TB-500 take to work?

Loading phase 2-4 weeks, then maintenance. Initial improvements often in 2-3 weeks.

Veterinary Disclaimer: Educational only. Consult a licensed vet before starting any supplement. Affiliate Disclosure